<configuration> 
   <configurationfile>file:///C:/Users/John/AppData/Local/Adobe/Adobe Substance 3D Designer/default_configuration.sbscfg</configurationfile> 
  </configuration>

import xml.etree.ElementTree as ElementTree 
import os 
 
##Example Python script for changing Substance 3D Designer user preference file## 
 
def SetConfigurationFile(p_ConfigPath): 
    #Check is the path passed as parameter exists. 
    if(os.path.isfile(p_ConfigPath)): 
        # replace backslashes by forwardslahes to ensure consistency 
        p_ConfigPath = p_ConfigPath.replace("\", "/") 
        #get Local Appadata path from Environment variables, construct full path to user_preferences.xml and check if it exists. 
        m_AppDataPath = os.environ.get('LOCALAPPDATA') 
        if m_AppDataPath != None: 
            m_UserPrefsPath = os.path.join(m_AppDataPath, str("Adobe/Adobe Substance 3D Designer/user_preferences.xml")) 
            if(os.path.isfile(m_UserPrefsPath)): 
                #read XML elementtree from file, find correct element until we get to the actual line that defines the configurationfile path 
                m_PrefsTree = ElementTree.parse(m_UserPrefsPath) 
                m_PrefsRoot = m_PrefsTree.getroot() 
                m_PrefsElement = m_PrefsRoot.find("preferences") 
                m_XMLError = True 
                if(m_PrefsElement != None): 
                    m_ConfigElement = m_PrefsElement.find("configuration") 
                    if(m_ConfigElement != None): 
                        m_ConfigFileElement = m_ConfigElement.find("configurationfile") 
                        if(m_ConfigFileElement != None): 
                            m_XMLError = False 
                            #Check if path is already set, to avoid double work 
                            if m_ConfigFileElement.text.replace("file:///","") == p_ConfigPath: 
                                print "configurationfile is already set to desired path. Aborting." 
                                return True 
                            else: 
                                #construct correctly formatted path, insert into elementtree 
                                m_ConfigPath = str("file:///" + p_ConfigPath) 
                                m_ConfigFileElement.text = m_ConfigPath 
 
                                #Write to file 
                                m_XMLString = str("<?xml version="1.0" encoding="UTF-8"?>n") + ElementTree.tostring(m_PrefsRoot, 'utf-8') 
                                m_File = open(m_UserPrefsPath,'w') 
                                m_File.write(m_XMLString) 
                                m_File.close() 
                                print "configuration file path succesfully changed!" 
                                return True 
                if m_XMLError: 
                    #if this flag was not set to false, we can assume something was missing or went wrong when walking through the XML 
                    print("Error: malformed content in user_preferences.xml!") 
                    return False 
            else: 
                print "Error: user_preferences.xml does not exist, try starting Substance 3D Designer first!" 
                return False 
        else: 
            print "Error: LocalAppData path returned None" 
            return False 
    else: 
        print "Error: Invalid Configuration File path!" 
        return False